Benadryl, a common antihistamine, can cause serious side effects like sedation, confusion, and even cardiac arrest, especially at high doses. Understanding these risks is crucial for safe use. 1
Wondering if its safe to take Benadryl every day? Learn about the risks, side effects and safer options for managing your allergies and sleep issues.

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Learn about the side effects of Benadryl (diphenhydramine), from common to rare, for consumers and healthcare professionals. Diphenhydramine can be harmful if people take it after having an allergic reaction to food, she said, because the drug best known by the brand name Benadryl makes them drowsy and can cause ... remedy once recommended by doctors has fallen out of favor because newer antihistamines pose fewer risks. Safer alternatives are available, she said, noting that diphenhydramine, the first-generation antihistamine in Benadryl and many other over-the-counter meds, poses particular safety risks to older people and young children.

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remedy once recommended by doctors has fallen out of favor because newer antihistamines pose fewer risks. Safer alternatives are available, she said, noting that diphenhydramine, the first-generation antihistamine in Benadryl and many other over-the-counter meds, poses particular safety risks to older people and young children.

When taking Benadryl, use caution driving, operating machinery, or performing other hazardous activities. Diphenhydramine may cause dizziness or drowsiness.How should I take Benadryl? Use Benadryl exactly as directed on the label, or as prescribed by your doctor.