Have a headache or a pulled muscle? Odds are over-the-counter (OTC) pain relievers like ibuprofen, aspirin, or acetaminophen will do the trick.
We reviewed dozens of pain relievers to identify the best of the best. We examined a range of factors, including strength, format, active ingredients, potential side effects, cost, and average customer reviews. All of these top-rated pain relievers can be purchased online at Amazon.com.

Discover the best pain reliever for your needs. Compare options, safety tips, and expert advice for safe, effective relief.

Over-the-counter (OTC) pain relievers help relieve pain and lower fevers. Find out how to choose between acetaminophen, ibuprofen, aspirin and others.

Discover the best over-the-counter drugs for arthritis relief, including NSAIDs like ibuprofen and acetaminophen. Manage joint pain and inflammation with expert-recommended OTC options.
Analyze detailed facts about 6 best over the counter pain relievers are they worth it. This central repository has aggregated 10 online sources and 8 media resources.
Over-the-Counter Pain Relief: Caution, Common Sense on All Drugs.With so many options at the drugstore, how do you know what over-the-counter pain reliever is the safest for you? Decoding OTC Drugs.